What is Multiple Sclerosis, how is it diagnosed, what is demyelination and remyelination, why is it important to track demyelination and remyelination in Multiple Sclerosis.

Discuss different MRI methods used to track demyelination and remyelination. How do they track them? What are the advantages and disadvantages of each? One of the methods should be magnetic transfer imaging. Mention signal intensity and if any biophysical methods are used for quantitative MRI methods.

Compare the different MRI methods used to track demyelination and remyelination in the methods section. What are the advantages and disadvantages of each?