Describe and explain the immunopathological mechanisms in, and treatment of, haemolytic disease of the new-born (HDN). Your answer should include the different blood group antigens involved.

Critically discuss the main differences between Chronic Myeloid Leukaemia and Chronic Lymphocytic Leukaemia.
Describe the haemophilias including their pathophysiology, investigation and treatment
Critically discuss the laboratory processes for distinguishing between. Iron deficiency anaemia and other forms of microcytic, hypochromic anaemia.
Criticaly discuss the relevance of the Major histocompatibility complex (MHC), and recent developments in transplantation
Discuss the disorders which may lead to thrombocytopenia including their pathophysiology and investigation.
Describe in detail the immunological basis to allograft transplantation and rejection.
Discuss the investigation of hereditary platelet disorders including their pathophysiology and the appropriate diagnostic. methods.