1. On what previous data/studies is this study based that brought about the reason for this study? Understanding the background should help you in stating the hypothesis of the study. Must answer all 4 questions below.

2. Why do you think this paper is important? What is the impact of the findings/how did it bring about a new idea to the field? Think about why the instructor selected this paper for you to read. You should end the synopsis with a statement of impact/how the paper advanced the field.

3. What are the major methods used in the study and the model system? Why did they use that model system? Could they have used another approach or model system?

4. What are the study conclusions/findings? Did the authors “deliver” on these conclusions, or not? Give reasons why/why not you think they proved their points. If not, what could they have done better, or added as an experiment?